Stereoselective Formation of Multiple Reaction Products by the Phosphotriesterase from Sphingobium sp. TCM1
نویسندگان
چکیده
منابع مشابه
Stereoselective detoxification of chiral sarin and soman analogues by phosphotriesterase.
The catalytic activity of the bacterial phosphotriesterase (PTE) toward a series of chiral analogues of the chemical warfare agents sarin and soman was measured. Chemical procedures were developed for the chiral syntheses of the S(P)- and R(P)-enantiomers of O-isopropyl p-nitrophenyl methylphosphonate (sarin analogue) in high enantiomeric excess. The R(P)-enantiomer of the sarin analogue (k(cat...
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ژورنال
عنوان ژورنال: Biochemistry
سال: 2020
ISSN: 0006-2960,1520-4995
DOI: 10.1021/acs.biochem.0c00089